Resistance of Human Ovarian Cancer Cells to Tumor Necrosis Factor α Is a Consequence of Nuclear Factor κB-Mediated Induction of Fas-Associated Death Domain-Like Interleukin-1β-Converting Enzyme-Like Inhibitory Protein

Author:

Xiao Chao Wu12,Yan Xiaojuan1,Li Yulian1,Reddy Shrikanth A. G.3,Tsang Benjamin K.1

Affiliation:

1. Department of Obstetrics and Gynecology and Cellular and Molecular Medicine (C.W.X., X.Y., Y.L., B.K.T.), Reproductive Biology Unit and Division of Gynecologic Oncology, University of Ottawa, Ottawa Health Research Institute, The Ottawa Hospital, Ottawa, Ontario, Canada K1Y 4E9;

2. Nutrition Research Division (C.W.X.), Food Directorate, Health Products and Food Branch, Health Canada, Banting Research Centre, Ottawa, Ontario, Canada K1A 0L2;

3. Department of GI Oncology and Digestive Diseases (S.A.G.R.), Division of Medicine, M. D. Anderson Cancer Center, University of Texas, Houston, Texas 77030

Publisher

The Endocrine Society

Subject

Endocrinology

Reference64 articles.

1. Cytokine-mediated regulation of ovarian function. Tumor necrosis factor α inhibits gonadotropin-supported ovarian androgen biosynthesis.;Andreani;J Biol Chem,1991

2. Transducers of life and death: TNF receptor superfamily and associated proteins.;Baker;Oncogene,1996

3. Ovarian cancer-induced immunosuppression: relationship to tumor necrosis factor-α (TNF-α) release from ovarian tissue.;Hassan;Anticancer Res,1999

4. Tumor necrosis factor and its receptors in human ovarian cancer. Potential role in disease progression.;Naylor;J Clin Invest,1993

5. Tumor necrosis factor expression by human ovarian carcinoma in vivo.;Takeyama;Cancer Res,1991

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