Prognostic Significance of the Ki-67 Labeling Index in Growth Hormone-Secreting Pituitary Adenomas

Author:

Fusco A.1,Zatelli M. C.2,Bianchi A.1,Cimino V.1,Tilaro L.1,Veltri F.1,Angelini F.3,Lauriola L.4,Vellone V.4,Doglietto F.5,Ambrosio M. R.2,Maira G.5,Giustina A.6,degli Uberti E. C.2,Pontecorvi A.1,De Marinis L.1

Affiliation:

1. Section of Endocrinology (A.F., A.B., V.C., L.T., F.V., A.P., L.D.M.), Università Cattolica del Sacro Cuore, 00168 Rome, Italy

2. Section of Endocrinology (M.C.Z., M.R.A., E.C.d.U.), Department of Biochemical Sciences and Advanced Therapies, University of Ferrara, 44100 Ferrara, Italy

3. Section of Laboratory of Vascular Biology and Genetics (F.A.), Università Cattolica del Sacro Cuore, 00168 Rome, Italy

4. Department of Internal Medicine, Institute of Pathology (L.L., V.V.), Università Cattolica del Sacro Cuore, 00168 Rome, Italy

5. Institute of Neurosurgery (F.D., G.M.), Università Cattolica del Sacro Cuore, 00168 Rome, Italy

6. Department of Internal Medicine (A.G.), University of Brescia, 25125 Brescia, Italy

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference20 articles.

1. Transsphenoidal surgery for acromegaly: endocrinological follow-up of 98 patients.;Shimon;Neurosurgery,2001

2. Long-term endocrinological follow-up evaluation in 115 patients who underwent transsphenoidal surgery for acromegaly.;Freda;J Neurosurg,1998

3. The outcome of surgery in 668 patients with acromegaly using current criteria of biochemical “cure.”;Nomikos;Eur J Endocrinol,2005

4. Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly.;Swearingen;J Clin Endocrinol Metab,1998

5. Long-term effects of depot long-acting somatostatin analog octreotide on hormone levels and tumor mass in acromegaly.;Colao;J Clin Endocrinol Metab,2001

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