Evidence that Shed Thyrotropin Receptor A Subunits Drive Affinity Maturation of Autoantibodies Causing Graves’ Disease

Author:

Mizutori Yumiko1,Chen Chun-Rong1,Latrofa Francesco1,McLachlan Sandra M.1,Rapoport Basil1

Affiliation:

1. Autoimmune Disease Unit, Cedars-Sinai Research Institute and David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90048

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference40 articles.

1. The thyrotropin receptor in Graves’ disease.;Rapoport;Thyroid,2007

2. Visualization of the thyrotropin receptor on the cell surface by potent autoantibodies.;De Forteza;J Clin Endocrinol Metab,1994

3. Thyrotropin receptor autoantibodies in serum are present at much lower levels than thyroid peroxidase autoantibodies: analysis by flow cytometry.;Jaume;J Clin Endocrinol Metab,1997

4. Thyroid stimulating monoclonal antibodies.;Sanders;Thyroid,2002

5. A monoclonal thyroid-stimulating antibody.;Ando;J Clin Invest,2002

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