A Glucocorticoid Receptor Gene Haplotype (TthIII1/ER22/23EK/9β) Is Associated with a More Aggressive Disease Course in Multiple Sclerosis-Reference-Cited by-同舟云学术

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A Glucocorticoid Receptor Gene Haplotype (TthIII1/ER22/23EK/9β) Is Associated with a More Aggressive Disease Course in Multiple Sclerosis

Published:2009-06-01 Issue:6 Volume:94 Page:2110-2114
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

van Winsen Lisa M. L.¹,Manenschijn Laura²,van Rossum Elisabeth F. C.²,Crusius Bart A.³,Koper Jan Willem²,Polman Chris H.¹,Uitdehaag Bernard M. J.¹⁴

Affiliation:

1. Departments of Neurology (L.M.L.v.W., C.H.P., B.M.J.U.), Vrije Universiteit Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

2. Department of Internal Medicine (L.M., E.F.C.v.R., J.W.K.), Erasmus Medical Center, Rotterdam 3000 DR, The Netherlands

3. Pathology (B.A.C.), Vrije Universiteit Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

4. Epidemiology and Biostatistics (B.M.J.U.), Vrije Universiteit Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/94/6/2110/9065387/jcem2110.pdf

Reference19 articles.

1. Corticosteroid resistance in a subpopulation of multiple sclerosis patients as measured by ex vivo dexamethasone inhibition of LPS induced IL-6 production.;DeRijk;J Neuroimmunol,2004

2. Impaired hypothalamic-pituitary-adrenal axis activity in patients with multiple sclerosis.;Ysrraelit;Neurology,2008

3. Sensitivity to glucocorticoids is decreased in relapsing remitting multiple sclerosis.;Winsen;J Clin Endocrinol Metab,2005

4. Decreased corticosensitivity in quiescent Crohn’s disease: an ex vivo study using whole blood cell cultures.;Franchimont;Dig Dis Sci,1999

5. Predicting therapeutic outcome in severe ulcerative colitis by measuring in vitro steroid sensitivity of proliferating peripheral blood lymphocytes.;Hearing;Gut,1999

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