Lgr4 Gene Regulates Corpus Luteum Maturation Through Modulation of the WNT-Mediated EGFR-ERK Signaling Pathway

Author:

Pan Hongjie12,Cui Hengxiang1,Liu Shijie1,Qian Yu1,Wu Haili1,Li Liang1,Guan Yuting1,Guan Xin1,Zhang Long1,Fan Heng-Yu3,Ma Yanlin4,Li Runsheng2,Liu Mingyao145,Li Dali1

Affiliation:

1. Shanghai Key Laboratory of Regulatory Biology (H.P., H.C., S.L., Y.Q., H.W., L.L., Y.G., X.G., L.Z., M.L., D.L.), Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China

2. Key Laboratory of Contraceptive Drugs and Devices of National Population and Family Planning Commission (H.P., R.L.), Shanghai Institute of Planned Parenthood Research, Shanghai 200032, China

3. Life Science Institute (H.-Y.F.), Zhejiang University, Hangzhou 310058, China

4. Hainan Provincial Key Laboratory for Human Reproductive Medicine and Genetic Research (Y.M.), Hainan Reproductive Medical Center, the Affiliated Hospital of Hainan Medical University, Haikou 570102, China

5. The Institute of Biosciences and Technology (M.L.), Texas A&M University Health Science Center, Houston, Texas 77030

Publisher

The Endocrine Society

Subject

Endocrinology

Reference56 articles.

1. The luteo-placental shift, the guardian of pre-natal life;Csapo;Postgrad Med J,1969

2. The corpus luteum insufficiency: a multifactorial disease;Hinney;J Clin Endocrinol Metab,1996

3. Ovulation: new dimensions and new regulators of the inflammatory-like response;Richards;Annu Rev Physiol,2002

4. Intact follicular maturation and defective luteal function in mice deficient for cyclin-dependent kinase-4;Moons;Endocrinology,2002

5. The role of gonadotropins in the follicular phase;Messinis;Ann N Y Acad Sci,2010

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