Continuous Glucose Monitoring to Diagnose Hypoglycemia Due to Late Dumping Syndrome in Children After Gastric Surgeries

Author:

Chesser Hannah1ORCID,Abdulhussein Fatema1,Huang Alyssa12ORCID,Lee Janet Y13ORCID,Gitelman Stephen E1ORCID

Affiliation:

1. Division of Pediatric Endocrinology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, United States

2. Division of Endocrinology and Diabetes, Department of Pediatrics, University of Washington, Seattle Children’s Hospital, Seattle, Washington, WA, United States

3. Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States

Abstract

Abstract Gastrostomy tubes (G-tubes) and Nissen fundoplication are common surgical interventions for feeding difficulties and gastroesophageal reflux disease in children. A potential yet often missed, complication of these procedures is dumping syndrome. We present 3 pediatric patients with postprandial hypoglycemia due to late dumping syndrome after gastric surgeries. All patients received gastrostomy tubes for feeding intolerance: 2 had Nissen fundoplication for gastroesophageal reflux disease, and 1 had tracheoesophageal repair. All patients underwent multiple imaging studies in an to attempt to diagnose dumping syndrome. Continuous glucose monitoring (CGM) was essential for detecting asymptomatic hypoglycemia and glycemic excursions occurring with feeds that would have gone undetected with point-of-care (POC) blood glucose checks. CGM was also used to monitor the effectiveness of treatment strategies and drive treatment plans. These cases highlight the utility of CGM in diagnosing postprandial hypoglycemia due to late dumping syndrome, which is infrequently diagnosed by imaging studies and intermittent POC blood glucose measurements.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institutes of Health

Publisher

The Endocrine Society

Subject

Endocrinology, Diabetes and Metabolism

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