1. Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom
2. Centre for Biomedical Modelling and Analysis, University of Exeter, Exeter EX2 5DW, United Kingdom
3. Engineering and Physical Sciences Research Council Centre for Predictive Modelling in Healthcare, University of Exeter, Exeter EX4 4QJ, United Kingdom
4. College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter EX4 4QF, United Kingdom
5. Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol BS1 3NY, United Kingdom