Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways

Author:

Sanchez-Garrido Miguel Angel12,Ruiz-Pino Francisco1234,Velasco Inmaculada12,Barroso Alexia124,Fernandois Daniela12,Heras Violeta12,Manfredi-Lozano Maria12,Vazquez Maria Jesus124,Castellano Juan Manuel124,Roa Juan1234,Pinilla Leonor1234,Tena-Sempere Manuel1234

Affiliation:

1. Instituto Maimónides de Investigación Biomédica de Cordoba, University of Cordoba, Cordoba, Spain

2. Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, Spain

3. Hospital Universitario Reina Sofia, Cordoba, Spain

4. CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Cordoba, Spain

Funder

Ministerio de Economía y Competitividad

Publisher

The Endocrine Society

Subject

Endocrinology

Reference50 articles.

1. World Health Organization Updates. 2016 obesity and overweight fact sheet. Available at: http://www.who.int/mediacentre/factsheets/fs311/en/. Accessed June 5, 2016.

2. Perinatal exposure to high-fat diet programs energy balance, metabolism and behavior in adulthood;Sullivan;Neuroendocrinology,2011

3. Prenatal nutrition and the risk of adult obesity: long-term effects of nutrition on epigenetic mechanisms regulating gene expression;Navarro;J Nutr Biochem,2017

4. Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms;Sánchez-Garrido;Endocrinology,2014

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