A Transgenic Mouse Model for Detection of Tissue-Specific Thyroid Hormone Action

Author:

Mohácsik Petra12,Erdélyi Ferenc3,Baranyi Mária4,Botz Bálint56,Szabó Gábor3,Tóth Mónika1,Haltrich Irén7,Helyes Zsuzsanna568,Sperlágh Beáta4,Tóth Zsuzsa7,Sinkó Richárd12,Lechan Ronald M910,Bianco Antonio C11,Fekete Csaba19,Gereben Balázs1

Affiliation:

1. Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary

2. János Szentágothai PhD School of Neurosciences, Semmelweis University, Budapest, Hungary

3. Medical Gene Technology Unit, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary

4. Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary

5. Department of Pharmacology and Pharmacotherapy, University of Pécs Medical School, Centre for Neuroscience, Pécs, Hungary

6. Molecular Pharmacology Research Team, János Szentágothai Research Centre, Pécs, Hungary

7. Second Department of Pediatrics, Faculty of Medicine, Semmelweis University, Budapest, Hungary

8. Hungarian Academy of Sciences–University of Pécs, Hungarian Brain Research Program, Chronic Pain Research Group, University of Pécs Medical School, Pécs, Hungary

9. Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Tupper Research Institute, Tufts Medical Center, Boston, Massachusetts

10. Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts

11. Division of Endocrinology and Metabolism, Rush University Medical Center, Chicago, Illinois

Funder

Hungarian National Brain Research Program

Hungarian Scientific Research

Publisher

The Endocrine Society

Subject

Endocrinology

Reference49 articles.

1. The mechanism of action of thyroid hormones;Zhang;Annu Rev Physiol,2000

2. Thyroid hormone receptors and resistance to thyroid hormone disorders;Ortiga-Carvalho;Nat Rev Endocrinol,2014

3. Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected beta type thyroid hormone receptor;Brent;J Biol Chem,1989

4. A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone;Glass;Nature,1987

5. Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells;Chatonnet;Proc Natl Acad Sci USA,2013

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