The Thyrotropin Receptor Hinge Region as a Surrogate Ligand: Identification of Loci Contributing to the Coupling of Thyrotropin Binding and Receptor Activation
Author:
Affiliation:
1. Thyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute and University of California Los Angeles School of Medicine, Los Angeles, California 90048
Publisher
The Endocrine Society
Subject
Endocrinology
Link
http://academic.oup.com/endo/article-pdf/153/10/5058/10388872/endo5058.pdf
Reference49 articles.
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3. Cell surface protein disulfide-isomerase is involved in the shedding of human thyrotropin receptor ectodomain.;Couët;Biochemistry,1996
4. The shed component of the TSH receptor is primarily a carboxyl terminal truncated form of the A subunit, not the entire A subunit.;Tanaka;Mol Cell Endocrinol,1999
5. Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor.;Chazenbalk;J Clin Invest,2002
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