1. Departments of Endocrinology and Metabolic Diseases (M.M.L.D., M.K., C.v.d.B., S.E.P., C.W.G.M.L.), Takasaki, Gunma 370-12, Japan
2. Pediatrics (M.K.), Leiden University Medical Center, 2333ZA Leiden, The Netherlands, Takasaki, Gunma 370-12, Japan
3. Pharmaceutical Research Laboratory, Kirin Brewery Co. Ltd. (T.Y.), 3 Miyahara, Takasaki, Gunma 370-12, Japan