Glucocorticoid Receptor-β and Receptor-γ Exert Dominant Negative Effect on Gene Repression But Not on Gene Induction

Author:

Taniguchi Yoshinori1,Iwasaki Yasumasa12,Tsugita Makoto1,Nishiyama Mitsuru1,Taguchi Takafumi1,Okazaki Mizuho1,Nakayama Shuichi1,Kambayashi Machiko1,Hashimoto Kozo3,Terada Yoshio1

Affiliation:

1. Department of Endocrinology, Metabolism, and Nephrology (Y.T., M.T., M.N., T.T., M.O., S.N., M.K., Y.T.), Kochi Medical School, Kochi University, Nankoku 783-8505, Japan

2. Department of Health Care Center (Y.I.), Kochi University, Kochi 780-8520, Japan

3. Department of Hosogi Hospital (K.H.), Kochi 780-8535, Japan

Publisher

The Endocrine Society

Subject

Endocrinology

Reference40 articles.

1. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids.;Bamberger;Endocr Rev,1996

2. Tissue glucocorticoid resistance/hypersensitivity syndrome.;Kino;J Steroid Biochem Mol Biol,2003

3. The physiology of human glucocorticoid receptor β (hGRβ) and glucocorticoid resistance.;Lewis-Tuffin;Ann NY Acad Sci,2006

4. Low glucocorticoid receptor α/β ratio in T-cell lymphoblastic leukemia.;Longui;Horm Metab Res,2000

5. Glucocorticoid receptor β splice variant expression in patients with high and low activity of systemic lupus erythematosus.;Piotrowski;Folia Histochem Cytobiol,2007

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