Altered Structure and Function of Reproductive Organs in Transgenic Male Mice Overexpressing Human Aromatase*

Author:

Li Xiangdong1,Nokkala Elina2,Yan Wei2,Streng Tomi1,Saarinen Niina1,Wärri Anni1,Huhtaniemi Ilpo2,Santti Risto1,Mäkelä Sari13,Poutanen Matti2

Affiliation:

1. Department of Anatomy (X.L., T.S., N.S., A.W., R.S., S.M.), Institute of Biomedicine, University of Turku, FIN-20520 Turku, Finland

2. Department of Physiology (E.N., W.Y., I.H., M.P.), Institute of Biomedicine, University of Turku, FIN-20520 Turku, Finland

3. Unit for Preventive Nutrition (S.M.), Karolinska Institute NOVUM, S-14157 Huddinge, Sweden

Publisher

The Endocrine Society

Subject

Endocrinology

Reference46 articles.

1. Sex steroid control of gonadotropin secretion in the human male. II. Effects of estradiol administration in normal and gonadotropin-releasing hormone-deficient men.;Finkelstein;J Clin Endocrinol Metab,1991

2. The direct pituitary effect of testosterone to inhibit gonadotropin secretion in men is partially mediated by aromatization to estradiol.;Bagatell;J Androl,1994

3. Sex differences and androgen-dependent regulation of aromatase (CYP19) mRNA expression in the developing and adult rat brain.;Lauber;J Steroid Biochem Mol Biol,1997

4. Estrogen receptor expression in developing epididymis, efferent ductules, and other male reproductive organs.;Cooke;Endocrinology,1991

5. Estrogen receptors, estradiol, and diethylstilbestrol in early development: the mouse as a model for the study of estrogen receptors and estrogen sensitivity in embryonic development of male and female reproductive tracts.;Greco;Endocr Rev,1993

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