The Biological Variation of Insulin Resistance in Polycystic Ovarian Syndrome

Author:

Jayagopal V.1,Kilpatrick E. S.2,Holding S.2,Jennings P. E.3,Atkin S. L.1

Affiliation:

1. Department of Medicine, University of Hull (V.J., S.L.A.), Hull, United Kingdom HU3 2RW

2. Department of Clinical Biochemistry and Immunology, Hull Royal Infirmary (E.S.K., S.H.), Hull, United Kingdom HU3 2RW

3. York District General Hospital (P.E.J.), Hull, United Kingdom HU3 2RW

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference22 articles.

1. Polycystic ovary syndrome;Franks;N Engl J Med,1995

2. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis;Dunaif;Endocr Rev,1997

3. Insulin stimulates androgen accumulation in incubations of ovarian stoma obtained from women with ovarian hyperandrogenism;Barbieri;J Clin Endocrinol Metab,1986

4. A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome;Nestler;J Clin Endocrinol Metab,1991

5. Insulin infusion amplifies 17α- hydroxycorticosteroid intermediates response to adrenocorticotropin in hyperandrogenic women: apparent relative impairment of 17,20-lyase activity;Moghetti;J Clin Endocrinol Metab,1996

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