Metformin Therapy in Obese Adolescents with Polycystic Ovary Syndrome and Impaired Glucose Tolerance: Amelioration of Exaggerated Adrenal Response to Adrenocorticotropin with Reduction of Insulinemia/Insulin Resistance

Author:

Arslanian Silva A.1,Lewy Vered1,Danadian Kapriel1,Saad Rola1

Affiliation:

1. Division of Pediatric Endocrinology, Metabolism, and Diabetes Mellitus, Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference39 articles.

1. Ovarian and adrenal function in polycystic ovary syndrome;Rosenfield;Endocrinol Metab Clin North Am,1999

2. Detection of functional ovarian hyperandrogenism in women with androgen excess;Ehrmann;N Engl J Med,1992

3. Adrenal androgen excess in the polycystic ovary syndrome: sensitivity and responsivity of the hypothalamic-pituitary-adrenal axis;Azziz;J Clin Endocrinol Metab,1998

4. Adrenal androgen excess in hyperandrogenism: relation to age and body mass;Moran;Fertil Steril,1999

5. Editorial: evidence that idiopathic functional adrenal hyperandrogenism is caused by dysregulation of adrenal steroidogenesis and that hyperinsulinemia may be involved;Rosenfield;J Clin Endocrinol Metab,1996

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