Human Growth Hormone Replacement in Adult Hypopituitary Patients: Long-Term Effects on Body Composition and Lipid Status—3-Year Results from the HypoCCS Database

Author:

Attanasio Andrea F.1,Bates Peter C.2,Ho Ken K. Y.3,Webb Susan M.4,Ross Richard J.5,Strasburger Christian J.6,Bouillon Roger7,Crowe Brenda8,Selander Keith8,Valle Domenico1,Lamberts Steven W. J.9,

Affiliation:

1. Eli Lilly & Co. (A.F.A., D.V.), 50019 Florence, Italy

2. Lilly Research Centre, Windlesham (P.C.B.), Surrey GU20 6PH, United Kingdom

3. Garvan Institute of Medical Research (K.K.Y.H.), Sydney NSW 2010, Australia

4. Hospital Santa Creu i Sant Pau (S.M.W.), 08025 Barcelona, Spain

5. Department of Medicine, Northern General Hospital (R.J.R.), Sheffield S5 7AU, United Kingdom

6. Ludwig-Maximilians-Universität (C.J.S.), München 80336, Germany

7. Laboratorium voor Experimentele Geneeskunde en Endocrinologie (R.B.), 3000 Leuven, Belgium

8. Eli Lilly & Co. (B.C., K.S.), Indianapolis, Indiana 46285

9. Ziekenhuis Dijkzigt (S.W.J.L.), 3015 GD Rotterdam, The Netherlands

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference31 articles.

1. Adult growth hormone (GH)-deficient patients demonstrate heterogeneity between childhood onset and adult onset before and during human GH treatment;Attanasio;J Clin Endocrinol Metab,1997

2. Growth hormone replacement therapy in adult hypopituitary patients with growth hormone deficiency: combined data from 12 European placebo-controlled clinical trials;Mardh;Endocrinol Metab,1994

3. Altered lipid pattern explains increased cardiovascular mortality in hypopituitary patients with growth hormone deficiency;Rosen;Clin Endocrinol (Oxf),1998

4. Quality of life, body composition and muscle strength in adult growth hormone deficiency: the influence of growth hormone replacement therapy for up to 3 years;Walleymahmed;Clin Endocrinol (Oxf),1997

5. Dynamics of lipoprotein metabolism in adult growth hormone deficiency;Christ;J Endocrinol Invest,1999

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