Effects of 12 Months of GH Treatment on Cortical and Trabecular Bone Content of IGFs and OPG in Adults with Acquired GH Deficiency: A Double-Blind, Randomized, Placebo-Controlled Study

Author:

Ueland T.1,Bollerslev J.1,Flyvbjerg A.2,Hansen T. B.3,Vahl N.4,Mosekilde L.5

Affiliation:

1. Department of Endocrinology (T.U., J.B.), National University Hospital, N-0027 Oslo, Norway;

2. Medical Research Laboratory M (A.F.), Aarhus University Hospital, DK-8000 Aarhus, Denmark;

3. Department of Endocrinology (T.B.H.), Odense University Hospital, DK-5000 Odense, Denmark;

4. Department of Internal Medicine and Endocrinology (N.V.), Aarhus Kommunehospital, DK-8000 Aarhus, Denmark;

5. Department of Cell Biology (L.M.), University of Aarhus, DK-8000 Aarhus, Denmark

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference30 articles.

1. Growth hormone treatment in adults with GH deficiency: effects on new biochemical markers of bone and collagen turnover.;Sartorio;J Endocrinol Invest,1993

2. Reduced bone mineral density in patients with adult onset growth hormone deficiency.;Holmes;J Clin Endocrinol Metab,1994

3. Increased fracture frequency in adult patients with hypopituitarism and GH deficiency.;Rosen;Eur J Endocrinol,1997

4. Preliminary study of the effects of growth hormone substitution therapy on bone mineral density and serum osteocalcin levels in adults with growth hormone deficiency;Thoren;Acta Endocrinol (Copenh),1993

5. The effect of growth hormone replacement therapy in hypopituitary adults on calcium and bone metabolism.;Beshyah;Clin Endocrinol (Oxf),1994

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