HLA-DQB1 Position 57 Defines Susceptibility to Isolated and Polyglandular Autoimmunity in Adults: Interaction With Gender

Author:

Kraus Anna U1ORCID,Penna-Martinez Marissa1,Shoghi Firouzeh1,Seidl Christian2,Meyer Gesine1,Badenhoop Klaus1

Affiliation:

1. Department of Internal Medicine I, Division of Endocrinology, Diabetes and Metabolism, University Hospital Frankfurt, Frankfurt, Germany

2. Institute of Transfusion Medicine and Immunohematology, Department of Transplantation Immunology and Immunogenetics, University Hospital Frankfurt, Frankfurt, Germany

Funder

Else Kröner-Fresenius-Stiftung

Deutsche Diabetes Gesellschaft

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference31 articles.

1. Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families;Concannon;Diabetes,2005

2. HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus;Todd;Nature,1987

3. II. Adrenal cortex and steroid 21-hydroxylase autoantibodies in children with organ-specific autoimmune diseases: markers of high progression to clinical Addison’s disease;Betterle;J Clin Endocrinol Metab,1997

4. Multiple loci in the HLA complex are associated with Addison’s disease;Skinningsrud;J Clin Endocrinol Metab,2011

5. Human histocompatibility leukocyte antigen-DQA1*0501 allele associated with genetic susceptibility to Graves’ disease in a Caucasian population;Yanagawa;J Clin Endocrinol Metab,1993

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