Alemtuzumab-Induced Thyroid Dysfunction Exhibits Distinctive Clinical and Immunological Features

Author:

Pariani Nadia1,Willis Mark2,Muller Ilaria3,Healy Sarah2,Nasser Taha2,McGowan Anne1,Lyons Greta1,Jones Joanne4,Chatterjee Krishna1,Dayan Colin3,Robertson Neil2,Coles Alasdair4,Moran Carla1

Affiliation:

1. University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, United Kingdom

2. Division of Psychological Medicine and Clinical Neuroscience, Department of Neurology, Cardiff University, University Hospital of Wales, Cardiff, United Kingdom

3. Thyroid Research Group, Cardiff University, University Hospital of Wales, Cardiff, United Kingdom

4. Department of Clinical Neurosciences, Addenbrooke’s Hospital, Cambridge, United Kingdom

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference25 articles.

1. Engineering multiple-domain forms of the therapeutic antibody CAMPATH-1H: effects on complement lysis;Greenwood;Ther Immunol,1994

2. Long term lymphocyte reconstitution after alemtuzumab treatment of multiple sclerosis;Hill-Cawthorne;J Neurol Neurosurg Psychiatry,2012

3. Alemtuzumab CARE-MS I 5-year follow-up: Durable efficacy in the absence of continuous MS therapy;Havrdova;Neurology,2017

4. Alemtuzumab CARE-MS II 5-year follow-up: Efficacy and safety findings;Coles;Neurology,2017

5. Alemtuzumab treatment of multiple sclerosis: long term safety and efficacy;Tuohy;J Neurol Neurosurg Psychiatry,2015

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