A Novel Interplay Between Irisin and PTH: From Basic Studies to Clinical Evidence in Hyperparathyroidism

Author:

Palermo Andrea1,Sanesi Lorenzo2,Colaianni Graziana2,Tabacco Gaia1,Naciu Anda Mihaela1,Cesareo Roberto3,Pedone Claudio4,Lelli Diana4,Brunetti Giacomina5,Mori Giorgio6,Colucci Silvia5,Manfrini Silvia1,Napoli Nicola1,Grano Maria2ORCID

Affiliation:

1. Unit of Endocrinology and Diabetes, Campus Bio-Medico University, Rome, Italy

2. Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy

3. UOS Malattie Metaboliche, Santa Maria Goretti Hospital, Latina, Italy

4. Unit of Geriatric, University Campus Bio-Medico, Rome, Italy

5. Department of Basic Medical Sciences, Neuroscience and Sense Organs, Section of Human Anatomy and Histology, University of Bari, Bari, Italy

6. Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference26 articles.

1. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis;Boström;Nature,2012

2. The myokine irisin increases cortical bone mass;Colaianni;Proc Natl Acad Sci USA,2015

3. Irisin prevents and restores bone loss and muscle atrophy in hind-limb suspended mice;Colaianni;Sci Rep,2017

4. Irisin levels correlate with bone mineral density in soccer players;Colaianni;J Biol Regul Homeost Agents,2017

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