Insights Into Local Orbital Immunity: Evidence for the Involvement of the Th17 Cell Pathway in Thyroid-Associated Ophthalmopathy-Reference-Cited by-同舟云学术

Insights Into Local Orbital Immunity: Evidence for the Involvement of the Th17 Cell Pathway in Thyroid-Associated Ophthalmopathy

Published:2018-12-03 Issue:5 Volume:104 Page:1697-1711
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Fang Sijie¹²³⁴,Huang Yazhuo¹²³⁴,Wang Ningjian⁵,Zhang Shuo¹²,Zhong Sisi¹²,Li Yinwei¹²,Sun Jing¹²,Liu Xingtong¹²,Wang Yang¹²,Gu Ping¹²,Li Bin²³⁴,Zhou Huifang¹²,Fan Xianqun¹²^ORCID

Affiliation:

1. Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

2. Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China

3. Shanghai Institute of Immunology, Shanghai JiaoTong University School of Medicine, Shanghai, China

4. Department of Immunology and Microbiology, Shanghai JiaoTong University School of Medicine, Shanghai, China

5. Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

Funder

National Natural Science Foundation of China

Shanghai Sailing Program

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/104/5/1697/28260592/jc.2018-01626.pdf

Reference46 articles.

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2. Current perspectives on the role of orbital fibroblasts in the pathogenesis of Graves’ ophthalmopathy;Dik;Exp Eye Res,2016

3. Regulation of orbital fibrosis and adipogenesis by pathogenic Th17 cells in Graves orbitopathy;Fang;J Clin Endocrinol Metab,2017

4. IL-17A exacerbates fibrosis by promoting the proinflammatory and profibrotic function of orbital fibroblasts in TAO;Fang;J Clin Endocrinol Metab,2016

5. Circulating and tissue-resident CD4+ t cells with reactivity to intestinal microbiota are abundant in healthy individuals and function is altered during inflammation;Hegazy;Gastroenterology,2017

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