A Polygenic Risk Score of Lipolysis-Increasing Alleles Determines Visceral Fat Mass and Proinsulin Conversion-Reference-Cited by-同舟云学术

A Polygenic Risk Score of Lipolysis-Increasing Alleles Determines Visceral Fat Mass and Proinsulin Conversion

Published:2019-01-10 Issue:4 Volume:104 Page:1090-1098
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Kempe-Teufel Daniela¹²³,Machicao Fausto²⁴,Machann Jürgen²³⁵,Böhm Anja¹²³,Schick Fritz²³⁵,Fritsche Andreas¹²³,Stefan Norbert¹²³,Hrabě de Angelis Martin²⁴⁶,Häring Hans-Ulrich¹²³,Staiger Harald²³⁷^ORCID

Affiliation:

1. Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University Tübingen, Tübingen, Germany

2. German Center for Diabetes Research (DZD), Neuherberg, Germany

3. Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany

4. Institute of Experimental Genetics, Helmholtz Center Munich, Neuherberg, Germany

5. Department of Diagnostic and Interventional Radiology, Section on Experimental Radiology, Eberhard Karls University Tübingen, Tübingen, Germany

6. Chair of Experimental Genetics, Technical University Munich, Neuherberg, Germany

7. Institute of Pharmaceutical Sciences, Department of Pharmacy and Biochemistry, Eberhard Karls University Tübingen, Tübingen, Germany

Funder

Bundesministerium für Bildung und Forschung

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/104/4/1090/27833080/jc.2018-02042.pdf

Reference24 articles.

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2. Lipotoxic endoplasmic reticulum stress, β cell failure, and type 2 diabetes mellitus;Biden;Trends Endocrinol Metab,2014

3. Toll-like receptor, lipotoxicity and chronic inflammation: the pathological link between obesity and cardiometabolic disease;Eguchi;J Atheroscler Thromb,2014

4. Fat depots, free fatty acids, and dyslipidemia;Ebbert;Nutrients,2013

5. Lipolysis in human adipocytes, effects of cell size, age and of regional differences;Engfeldt;Horm Metab Res Suppl,1988

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