Proparathyroid Hormone Processing by the Proprotein Convertase-7: Comparison with Furin and Assessment of Modulation of Parathyroid Convertase Messenger Ribonucleic Acid Levels by Calcium and 1,25-Dihydroxyvitamin D3*

Author:

Canaff Lucie1,Bennett Hugh P. J.1,Hou Yu1,Seidah Nabil G.123,Hendy Geoffrey N.4

Affiliation:

1. Department of Medicine (L.C., H.P.J.B., Y.H., G.N.H.), McGill University and Royal Victoria Hospital, Montréal, Québec H3A 1A1, Canada

2. Departments of Physiology (G.N.H.), McGill University and Royal Victoria Hospital, Montréal, Québec H3A 1A1, Canada

3. Departments of Human Genetics (G.N.H.), McGill University and Royal Victoria Hospital, Montréal, Québec H3A 1A1, Canada

4. the J. A. DeSeve Laboratory of Biochemical Neuroendocrinology (N.G.S.), Clinical Research Institute of Montréal, Université de Montréal, Montréal, Québec H2W 1R7, Canada

Publisher

The Endocrine Society

Subject

Endocrinology

Reference59 articles.

1. Hendy GN, Arnold A 1996 Molecular basis of PTH overexpression. In: Bilezikian JP, Raisz LG, Rodan GA (eds) Principals of Bone Biology. Academic Press, San Diego, pp 757–767

2. Yang KH, Stewart AF 1996 Parathyroid hormone-related protein: the gene, its mRNA species, and protein products. In: Bilezikian JP, Raisz LG, Rodan GA (eds) Principals of Bone Biology. Academic Press, San Diego, pp 347–362

3. Pre-proparathyroid hormone: a direct translation product of parathyroid messenger RNA.;Kemper;Proc Natl Acad Sci USA,1974

4. Parathyroid hormone biosynthesis. Correlation of conversion of biosynthetic precursors with intracellular protein migration as determined by electron microscope autoradiography.;Habener;J Cell Biol,1979

5. Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes.;Van de Ven;Mol Biol Rep,1990

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