Distinct Sites of Insulin-Like Growth Factor (IGF)-II Expression and Localization in Lesioned Rat Brain: Possible Roles of IGF Binding Proteins (IGFBPs) in the Mediation of IGF-II Activity**This work was supported by grants (to A.L. and M.B.) from The Wellcome Trust and The International Spinal Research Trust.

Author:

Walter H. J.1,Berry M.2,Hill D. J.3,Cwyfan-Hughes S.4,Holly J. M. P.4,Logan A.1

Affiliation:

1. Department of Medicine (H.J.W., A.L.), University of Birmingham, Birmingham B15 2TT, United Kingdom;

2. Department of Anatomy and Cell Biology (M.B.), UMDS, Guy’s Hospital, London SE1 9RT, United Kingdom;

3. Department of Medicine, Physiology and Paediatrics (D.J.H.), Lawson Research Institute, London, Ontario N6A 4V2, Canada;

4. Department of Surgery (S.C.-H., J.M.P.H.), University of Bristol, Bristol, BS2 8HW, United Kingdom

Publisher

The Endocrine Society

Subject

Endocrinology

Reference48 articles.

1. Growth factors in CNS repair and regeneration.;Logan;Prog Growth Factor Res,1995

2. Cellular responses to penetrating CNS injury.;Berry,1998

3. Insulin-like growth factor II expression in the developing human brain.;McKelvie;J Neuropathol Exp Neurol,1992

4. Co-ordinated pattern of expression and localization of insulin-like growth factor (IGF)-II and IGF binding protein-2 in the adult rat brain.;Logan;Endocrinology,1994

5. Expression of IGF-I and -II mRNA in the brain and craniofacial region of the rat fetus.;Ayer-le-Lievre;Development,1991

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