Mitogen-Activated Protein Kinase Cascade Is Involved in Endothelin-1-Induced Rat Puerperal Uterine Contraction

Author:

Kimura Akiko1,Ohmichi Masahide1,Takeda Takashi1,Kurachi Hirohisa1,Ikegami Hiromasa1,Koike Koji2,Masuhara Kanji1,Hayakawa Jun1,Kanzaki Tohru1,Kobayashi Mamoru3,Akabane Masuo3,Inoue Masaki2,Miyake Akira1,Murata Yuji1

Affiliation:

1. Department of Obstetrics and Gynecology (A.K., M.O., T.T., H.K., H.I., K.M., J.H., T.K., A.M., Y.M.), Osaka University Medical School, Suita, Osaka 565, Japan

2. Department of Obstetrics and Gynecology (K.K., M.I.), Kanazawa University Medical School, Kanazawa, Ishikawa 920, Japan

3. Kissei Pharmaceutical Company Ltd (M.K., M.A.), Minamiazumi, Nagano 399–83, Japan

Publisher

The Endocrine Society

Subject

Endocrinology

Reference83 articles.

1. A novel potent vasoconstrictor peptide produced by vascular endothelial cells;Yanagisawa;Nature,1988

2. Contractile effects of prostaglandins, oxytocin and endothelin-1 in human myometrium in vitro: refractoriness of myometrial tissue of pregnant women to prostaglandin E2 and F2 alpha;Word;J Clin Endocrinol Metab,1992

3. Contractile effects of endothelin-1 and endothelin-3 on myometrium and small intramyometrial arteries of pregnant women at term;Wolff;Gynecol Obstet Invest,1993

4. Endothelin stimulates DNA synthesis in Swiss 3T3 cells;Brown;Biochem J,1989

5. The endothelin peptides, ET-1 ET-2, ET-3 and sarafotoxin S6b, are co-mitogenic with platelet-derived growth factor for vascular smooth muscle cells;Weissberg;Atherosclerosis,1990

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