Pharmacokinetics of IGF-1 in PAPP-A2-Deficient Patients, Growth Response, and Effects on Glucose and Bone Density-Reference-Cited by-同舟云学术

Pharmacokinetics of IGF-1 in PAPP-A2-Deficient Patients, Growth Response, and Effects on Glucose and Bone Density

Published:2017-09-28 Issue:12 Volume:102 Page:4568-4577
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Cabrera-Salcedo Catalina¹²,Mizuno Tomoyuki²³,Tyzinski Leah¹,Andrew Melissa¹,Vinks Alexander A²³,Frystyk Jan⁴,Wasserman Halley¹²,Gordon Catherine M¹²,Hwa Vivian¹²,Backeljauw Philippe¹²,Dauber Andrew¹²

Affiliation:

1. Division of Endocrinology, Cincinnati Children’s Hospital Medical Center

2. Department of Pediatrics, University of Cincinnati College of Medicine

3. Clinical Pharmacology, Cincinnati Children’s Hospital Medical Center

4. Department of Clinical Medicine, Faculty of Health, Aarhus University Hospital, Denmark

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institutes of Health

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/102/12/4568/22224586/jc.2017-01411.pdf

Reference31 articles.

1. Circulating levels of IGF-1 directly regulate bone growth and density;Yakar;J Clin Invest,2002

2. The role of PAPP-A in the IGF system: location, location, location;Oxvig;J Cell Commun Signal,2015

3. Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor–binding protein-5 proteinase;Overgaard;J Biol Chem,2001

4. Regulation of insulin-like growth factor (IGF) bioactivity by sequential proteolytic cleavage of IGF binding protein-4 and -5;Laursen;Mol Endocrinol,2007

5. Mutations in pregnancy-associated plasma protein A2 cause short stature due to low IGF-I availability;Dauber;EMBO Mol Med,2016

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