Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol

Author:

Nagaraj Vini1,Kazim Abdulla S.1,Helgeson Johan1,Lewold Clemens1,Barik Satadal1,Buda Pawel1,Reinbothe Thomas M.1,Wennmalm Stefan2,Zhang Enming1,Renström Erik1

Affiliation:

1. Department of Clinical Sciences Malmö (V.N., A.S.K., J.H., C.L., S.B., P.B., T.M.R., E.Z., E.R.), Lund University Diabetes Centre, Lund University, SE-20502 Malmö, Sweden

2. Science for Life Laboratory (S.W.), KTH Royal Institute of Technology, SE-171 77 Stockholm, Sweden

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference50 articles.

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3. Lipid sorting in epithelial cells;Simons;Biochemistry,1988

4. Lipid rafts and signal transduction;Simons;Nat Rev Mol Cell Biol,2000

5. Lipid rafts and the regulation of exocytosis;Salaun;Traffic,2004

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