Low Expression of the Cell Cycle Inhibitor p27Kip1 in Normal Corticotroph Cells, Corticotroph Tumors, and Malignant Pituitary Tumors

Author:

Lidhar Kulbir1,Korbonits Márta2,Jordan Suzanne1,Khalimova Zamira2,Kaltsas Gregory2,Lu Xin3,Clayton Richard N.4,Jenkins Paul J.2,Monson John P.2,Besser G. Michael2,Lowe David G.1,Grossman Ashley B.2

Affiliation:

1. Departments of Histopathology (K.L., S.J., D.G.L.), London EC1A 7BE

2. Endocrinology (M.K., Z.K., G.K., P.J.J., J.P.M., G.M.B., A.B.G.), St. Bartholomew’s Hospital, London EC1A 7BE

3. Ludwig Institute for Cancer Research (X.L.), St. Mary’s Hospital, London W2 1PG, United Kingdom

4. Centre for Cell Molecular Medicine (R.N.C.), University of Keele, Stoke-on-Trent ST4 7Q3

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference45 articles.

1. Clonal origin of pituitary adenomas.;Herman;J Clin Endocrinol Metab,1990

2. GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumors.;Landis;Nature,1989

3. Pituitary tumor pathogenesis.;Shimon;J Clin Endocrinol Metab,1997

4. Malignant pituitary tumors.;Kaltsas;Pituitary,1998

5. G1 phase progression: cycling on cue.;Cell,1991

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