A Novel Retro-Inverso Gonadotropin-Releasing Hormone (GnRH) Immunogen Elicits Antibodies That Neutralize the Activity of Native GnRH-Reference-Cited by-同舟云学术

A Novel Retro-Inverso Gonadotropin-Releasing Hormone (GnRH) Immunogen Elicits Antibodies That Neutralize the Activity of Native GnRH

Published:2003-07-01 Issue:7 Volume:144 Page:3262-3269
ISSN:0013-7227
Container-title:Endocrinology
language:en
Short-container-title:

Author:

Fromme B.¹,Eftekhari P.²³,van Regenmortel M.⁴,Hoebeke J.²,Katz A.¹,Millar R.¹⁵

Affiliation:

1. Division of Medical Biochemistry, University of Cape Town Faculty of Health Sciences (B.F., A.K., R.M.), 7925 Observatory, South Africa

2. Immunochemistry Laboratory (UPR9021), Institut de Biologie Moleculaire et Cellulaire du Centre National de la Recherche Scientifique (P.E., M.R., J.H.), 67084 Strasbourg, France

3. Institute of Pharmacology School of Medicine (P.E.), 67000 Strasbourg, France

4. School of Biotechnology, Centre National de la Recherche Scientifique, Strasbourg University (M.V.R.), Illkirch 67400, France

5. Human Reproductive Sciences Unit, University of Edinburgh (R.M.), Edinburgh, United Kingdom EH16 4SB; and Forenap Therapeutic Discovery

Publisher

The Endocrine Society

Subject

Endocrinology

Link

http://academic.oup.com/endo/article-pdf/144/7/3262/11129053/endo3262.pdf

Reference25 articles.

1. Gonadotrophin-releasing hormone-diversity of functions and clinical applications.;Millar;S Afr Med J,1987

2. Clinical uses of gonadotropin-releasing hormone analogues.;Casper;Can Med Assoc J,1991

3. Antigenic and immunogenic properties of totally synthetic peptide-based anti-fertility vaccines.;Ghosh;Int Immunol,1999

4. Highly immunogenic and fully synthetic peptide-carrier constructs targetting GnRH.;Beekman;Vaccine,1999

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