Reproductive Disturbances, Pituitary Lactotrope Adenomas, and Mammary Gland Tumors in Transgenic Female Mice Producing High Levels of Human Chorionic Gonadotropin

Author:

Rulli Susana B.1,Kuorelahti Aino1,Karaer Öznur2,Pelliniemi Lauri J.2,Poutanen Matti1,Huhtaniemi Ilpo1

Affiliation:

1. Department of Physiology (S.B.R., A.K., M.P., I.H.), University of Turku, FIN-20520 Turku, Finland

2. Laboratory of Electron Microscopy (O.K., L.J.P.), University of Turku, FIN-20520 Turku, Finland

Publisher

The Endocrine Society

Subject

Endocrinology

Reference59 articles.

1. Molecular biology of the pituitary gonadotropins;Gharib;Endocr Rev,1990

2. The beginning of a new era in reproductive biology and medicine: expression of low levels of functional luteinizing hormone/human chorionic gonadotropin receptors in non-gonadal tissues;Rao;J Physiol Pharmacol,1996

3. Elevated luteinizing hormone induces expression of its receptor and promotes steroidogenesis in the adrenal cortex;Kero;J Clin Invest,2000

4. Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function;Themmen;Endocr Rev,2000

5. Determinants of ovarian cancer risk. II. Inferences regarding pathogenesis;Cramer;J Natl Cancer Inst,1983

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