1. Departments of Cardiovascular Medicine (S.J., I.S., A.K.), Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan
2. Laboratory of Anatomy (C.N.M.), Hokkaido University Graduate School of Veterinary Medicine, Sapporo 060-8638, Japan
3. Pharmacology (N.M., H.T., Y.H.), Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan
4. Department of Environmental Medicine and Informatics (A.S.), Hokkaido University Graduate School of Environmental Earth Science, Sapporo 060-8638, Japan