1. Department of Vascular and Metabolic Diseases (E.B., A.S., A.F., J.M., E.S., E.N.), Switzerland
2. Department of Discovery Chemistry (J.B., M.S., B.G., A.R., A.R., B.K., H.P.M.), Switzerland
3. Department of Exploratory Development (M.M.), Pharmaceuticals Division, Fa. Hoffmann-La Roche AG, CH-4070 Basel, Switzerland