Treatment with Flutamide, Metformin, and Their Combination Added to a Hypocaloric Diet in Overweight-Obese Women with Polycystic Ovary Syndrome: A Randomized, 12-Month, Placebo-Controlled Study
Author:
Affiliation:
1. Division of Endocrinology, Department of Internal Medicine, and Center for Applied Biomedical Research, S. Orsola-Malpighi Hospital, University of Bologna, 40138 Bologna, Italy
Publisher
The Endocrine Society
Subject
Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism
Link
http://academic.oup.com/jcem/article-pdf/91/10/3970/9063211/jcem3970.pdf
Reference45 articles.
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2. Clinical and hormonal characteristics of obese amenorrheic hyperandrogenic women before and after weight loss;Pasquali;J Clin Endocrinol Metab,1989
3. 17α-Hydroxyprogesterone responses to leuprolide and serum androgens in obese women with and without polycystic ovary syndrome after dietary weight loss;Jakubowicz;J Clin Endocrinol Metab,1997
4. Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17α activity and serum androgens;Nestler;J Clin Endocrinol Metab,1997
5. Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome;Nestler;N Engl J Med,1998
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