1. Graduate Schools of Medicine (R.A., I.S., M.M.), Osaka 565-0871, Japan
2. Howard Hughes Medical Institute and Department of Pharmacology (A.I.S., D.J.M.), University of Texas Southwestern Medical Center, Dallas, Texas 75390-9050
3. Institute of Biomaterials and Bioengineering and School of Biomedical Science (K.Y., S.Y.), Tokyo Medical and Dental University, Tokyo 101-0062, Japan
4. Frontier Biosciences (I.S., M.M.), Osaka University, Osaka 565-0871, Japan