Liquid Chromatography–Tandem Mass Spectrometry Analysis of Human Adrenal Vein 19-Carbon Steroids Before and After ACTH Stimulation

Author:

Rege Juilee1,Nakamura Yasuhiro2,Satoh Fumitoshi3,Morimoto Ryo3,Kennedy Michael R.4,Layman Lawrence C.5,Honma Seijiro6,Sasano Hironobu2,Rainey William E.7

Affiliation:

1. Department of Physiology (J.R.), Augusta, Georgia 30912

2. Department of Pathology (Y.N., H.S.), Sendai 980-8575, Japan

3. Division of Nephrology, Endocrinology, and Vascular Medicine, Department of Medicine (F.S., R.M.), Tohoku University School of Medicine, Sendai 980-8575, Japan

4. Harbor BioSciences, Inc (M.R.K.), San Diego, California 92122

5. Section of Reproductive Endocrinology, Infertility, and Genetics, Department of Obstetrics and Gynecology, Institute of Molecular Medicine and Genetics, Neuroscience Program (L.C.L.), Georgia Health Sciences University, Augusta, Georgia 30912

6. Aska Pharma Medical Co. Ltd (S.H.), Kawasaki 213-8522, Japan

7. Department of Molecular and Integrative Physiology (W.E.R.), University of Michigan Medical School, Ann Arbor, Michigan 48109-5622

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference24 articles.

1. The secretion of sex hormones by the adrenal gland;Short;Biochem Soc Symp,1960

2. Androgen release and synthesis in vitro by human adult adrenal glands;Cohn;J Clin Invest,1963

3. The biosynthesis of adrenocortical hormones by the human adrenal gland in vitro;Lombardo;Endocrinology,1959

4. The zona reticularis is the site of biosynthesis of dehydroepiandrosterone and dehydroepiandrosterone sulfate in the adult human adrenal cortex resulting from its low expression of 3β-hydroxysteroid dehydrogenase;Endoh;J Clin Endocrinol Metab,1996

5. Studies to confirm the source of 11β-hydroxyandrostenedione;Holownia;J Steroid Biochem Mol Biol,1992

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