1. Departments of Molecular and Genetic Medicine (H.On., H.Os.), Ehime, 791-0295 Japan
2. Ehime Proteo-Medicine Research Center (H.On., H.Os.), Ehime University, To-on, Ehime, 791-0295 Japan
3. Dermatology (M.T., K.H.), Ehime University Graduate School of Medicine, To-on, Ehime, 791-0295 Japan
4. Department of Metabolic Medicine (A.I.), Graduate School of Medicine, Osaka University, Osaka, 565-0871 Japan
5. Department of Internal Medicine (I) (T.H.), Osaka Medical College, Osaka, 569-8686 Japan;
6. Third Department of Internal Medicine (T.K.), Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, 409-3898 Japan
7. Department of Dermatology (Y.K.), Kyorin University School of Medicine, Tokyo, 181-8611 Japan;
8. Doctoral Program in Life System Medical Sciences (J.O.), Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, 305-8577 Japan
9. Shiraishi Hospital Diabetes Center (H.M.), Ehime, 794-0041 Japan