Common Genetic Variants in Peroxisome Proliferator-Activated Receptor-γ (PPARG) and Type 2 Diabetes Risk Among Women's Health Initiative Postmenopausal Women

Author:

Chan Kei Hang K.12,Niu Tianhua3,Ma Yunsheng4,You Nai-chieh Y.1,Song Yiqing5,Sobel Eric M.6,Hsu Yi-Hsiang78,Balasubramanian Raji9,Qiao Yongxia4,Tinker Lesley10,Liu Simin121112

Affiliation:

1. Program on Genomics and Nutrition (K.H.K.C., N.Y.Y., S.L.), Los Angeles, California 90095

2. Department of Epidemiology, and Center for Metabolic Disease Prevention (K.H.K.C., N.Y.Y., S.L.), Los Angeles, California 90095

3. Department of Biostatistics and Bioinformatics (T.N.), Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana 70112

4. Department of Medicine (Y.M., Y.Q.), Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Boston, Massachusetts 01655

5. Department of Medicine (Y.S.), Harvard School of Public Health, Boston, Massachusetts 02215

6. Department of Human Genetics (E.M.S.), Los Angeles, California 90095

7. Hebrew SeniorLife Institute for Aging Research (Y.-H.H.), Department of Medicine, Division of Gerontology, Beth Israel Deaconess Medical and Harvard Medical School, Boston, Massachusetts 02131

8. Molecular and Integrative Physiological Sciences Program (Y.-H.H.), Harvard School of Public Health, Boston, Massachusetts 02115

9. Department of Public Health (R.B.), Division of Biostatistics, University of Massachusetts-Amherst, Amherst, Massachusetts 01003

10. Fred Hutchinson Cancer Research Center (L.T.), Seattle, Washington 98109

11. Department of Medicine (S.L.), Los Angeles, California 90095

12. Jonsson Comprehensive Cancer Center (S.L.), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference19 articles.

1. The many faces of PPARγ: anti-inflammatory by any means?;Szanto;Immunobiology,2008

2. PPARs and their metabolic modulation: new mechanisms for transcriptional regulation?;Ahmed;J Intern Med,2007

3. From bench to bedside: novel mechanisms and therapeutic advances through the development of selective peroxisome proliferator-activated receptor γ modulators;Blackburn;Am J Clin Nutr

4. Peroxisome proliferator-activated receptor translational research and clinical experience;Cheatham;Am J Clin Nutr

5. A role for central nervous system PPAR-γ in the regulation of energy balance;Ryan;Nat Med

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