Affiliation:
1. Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation
2. Federal Scientific Center of Hygiene named after F.F. Erisman of the Federal Service for Supervision in Protection of the Rights of Consumer and Man Wellbeing
Abstract
Introduction. Electric insecticide vaporizer is a heating device, powered by the mains, when turned on this, the insecticidal agent, including the active substance, evaporates into the air of the treated room. The population uses an electric insecticide vaporizer during the warm season to destroy flying blood-sucking insects, which, in addition to epidemiological danger, creates psychological discomfort at night. Highly volatile pyrethroids are used as active ingredients in insecticidal electric vaporizer agents, which have an adverse effect on the nervous system, liver and urinary system. It is also becoming urgent the problem of air pollution indoor, especially for children. Materials and methods. Toxicological methods for assessing the danger of using insecticidal agents; biochemical methods for the study of blood serum. Results. There was studied a long-term inhalation effect of an electric insecticide vaporizer based on transfluthrin on the functional state of white rats. The agent was established to have an effect on the number of eosinophils in the blood, indicating to the development of allergic responses in the body of rats; affects the function of the nervous system, which confirms the literature data; disrupts metabolic processes in the liver, manifested in a change in individual indicators (carbohydrate, protein metabolism, creatinine synthesis). Limitations. In our study, there are no data on the study of organ tissues, nor have we studied the processes of cell damage as a result of oxidative stress. Conclusion. Based on the conducted studies, physiological and biochemical biomarkers of the effect of an electric vaporizer with transfluthrin were established. Continuous long-term use of electric insecticide vaporizer can have a harmful effect on the body. The use of these products in ventilated areas according to the consumption rate is safe. To identify the toxic effect of inhalation exposure to transfluthrin, 80 outbred white rats were examined in terms of parameters characterizing the functions of the nervous, respiratory systems, liver, kidneys, and peripheral blood composition.
Publisher
Federal Scientific Center for Hygiene F.F.Erisman
Subject
Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pollution,General Medicine
Reference29 articles.
1. Khlyzova T.A. Daily activity dynamics of different species (Diptera, Culicidae) of blood-sucking mosquitoes in the south of the Tyumen Region. Rossiyskiy parazitologicheskiy zhurnal. 2020; 14(1): 17–28. https://doi.org/10.31016/1998-8435-2020-14-1-17-28 (in Russian)
2. Barashkova A.I., Reshetnikov A.D. Ecology of bloodsucking mosquitoes (Diptera, Culicidae) of Central Taiga Zone. Izvestiya Samarskogo nauchnogo tsentra Rossiyskoy akademii nauk. 2012; 14(5): 143. (in Russian)
3. Sharkov A.A. Blood-Sucking Mosquitoes (Diptera, Culicidae) of the Murmansk Region [Krovososushchie komary (Diptera, Culicidae) Murmanskoy oblasti]. Petrozavodsk: Kareliya; 1980. (in Russian)
4. Mezenev N.P. The influence of external factors on the activity of mosquito attacks and its daily rhythm in the Arctic. Parazitologiya. 1971; 5(3): 254. (in Russian)
5. Monroe A., Moore S., Okumu F., Kiware S., Lobo N.F., Koenker H., et al. Methods and indicators for measuring patterns of human exposure to malaria vectors. Malar. J. 2020; 19(1): 207. https://doi.org/10.1186/s12936-020-03271-z