Mechanisms of physiological and toxic effects of lithium salts on the body (literature review)

Author:

Gorokhova Larisa G.1ORCID,Zhukova Anna G.1ORCID,Mikhailova Nadezhda N.2ORCID,Korsakova Tatyana G.2ORCID

Affiliation:

1. Research Institute for Complex Problems of Hygiene and Occupational Diseases; Kuzbass Humanitarian and Pedagogical Institute of the “Kemerovo State University”

2. Research Institute for Complex Problems of Hygiene and Occupational Diseases

Abstract

The study of the influence of various chemical elements on the human body is an important direction because it allows determining the patterns of the distribution and migration of these elements in tissues, as well as their role in the development of specific diseases. Among inorganic chemical compounds, a special place is occupied by lithium salts, which are widely used in industry, agriculture, and medicine. The search and selection of literature sources to identify the physiological effects and characteristics of the toxic effects of lithium salts on the human body and experimental animals was carried out using the bibliographic databases: Scopus, MedLine, Web of Science, PubMed, The Cochrane Library, RSCI, Cyberleninka. Data analysis has showed lithium salts to be classified as moderately hazardous substances (hazard class 3) and in high concentrations have a damaging effect on the functions of the nervous system, kidneys, thyroid and parathyroid glands.

Publisher

Federal Scientific Center for Hygiene F.F.Erisman

Reference68 articles.

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