Mechanism of Action Efficacy and Safety of the Topical Combination of Active Vitamin D3 and Steroid in Psoriasis Pathology
Author:
Affiliation:
1. LEO Pharma K.K. Medical Affairs
2. Department of Dermatology, Hamamatsu University School of Medicine
Publisher
Western Japan Division of JDA
Subject
Dermatology
Link
https://www.jstage.jst.go.jp/article/nishinihonhifu/81/2/81_93/_pdf
Reference23 articles.
1. 1) Hino R, Kabashima R, Kawakami C, Sugita K, Nakamura M, Tokura Y : Circulating Th17 cell fluctuation in psoriatic patients treated with topical calcipotriol and betamethasone butyrate propionate. J Eur Acad Dermatol Venereol, 2011 ; 25 : 242-244.
2. 2) Hawkes JE, Chan TC, Krueger JG : Psoriasis pathogenesis and the development of novel targeted immune therapies. J Allergy Clin Immunol, 2017 ; 1 40 : 645-653.
3. 3) Lowes MA, Russell CB, Martin DA, Towne JE, Krueger JG : The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses. Trends Immunol, 2013 ; 34 : 174-181.
4. 4) Hawkes JE, Yan BY, Chan TC, Krueger JG : Discovery of the IL-23/IL-17 signaling pathway and the treatment of psoriasis. J Immunol, 2018 ; 201 : 1605-1613.
5. 5) Daudén E, Bewley A, Lambert J, Girolomoni G, Cambazard F, Reich K : Expert recommendations : the use of the fixed combination calcipotriol and betamethasone dipropionate gel for the topical treatment of psoriasis. J Eur Acad Dermatol Venereol, 2014 ; 28 : 22-32.
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