Abstract
Today, when it comes to geriatric syndromes, scientists pay an extraordinary amount of attention to sarcopenia, due to its significant medical
and social consequences of the condition. It has been established that in
the presence of sarcopenia the risk of falls and fractures increases, daily
physical activity decreases. It is associated with pathologies of the cardiovascular system and respiratory organs, and cognitive impairment;
quality of life is made worse, patients with sarcopenia need extraneous
help. The prevalence of sarcopenia varies significantly (5-70%) depending on age, gender and ethnicity. In 2009, the European Working Group
on Sarcopenia in Older People (EWGSOP) was set up to actively develop definitions and diagnostic criteria for sarcopenia. In 2010, a first
consensus was published on the definition and diagnosis of sarcopenia,
in 2019, the consensus was updated. According to the latest revision
of EWGSOP consensus, sarcopenia is a progressive and generalized
skeletal muscle disease that is associated with an increased risk of falls,
fractures, impaired physical activity and mortality. The review of the
EWGSOP consensus is driven by the significant increase of the number
of sarcopenia studies in the world, and the emergence of new data on
the epidemiology, mechanisms of development, diagnosis, prevention
and treatment of the condition. To date, sarcopenia is considered a
disorder. In 2016, the diagnosis of sarcopenia was formally included in
the supplemented 10th International Classification of Diseases under
the code M 62.84. This article presents data on the epidemiology of
sarcopenia, describes the mechanisms of development, outlines the latest recommendations for the diagnosis of sarcopenia according to the
2019 EWGSOP consensus, as well as methods for the prevention and
treatment of the disease.
Key words: sarcopenia, muscle, age.
For citation: Povoroznyuk VV, Dzerovych NI. Sarcopenia (LITERATURE REVIEW). Journal of the National Academy of Medical Sciences
of Ukraine. 2019;25(3):321–31
Publisher
National Academy of Medical Sciences of Ukraine
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