Young adults’ attitudes toward COVID-19 are vital for their adherence to control measures taken by the government to break the chain of contamination. This study aims to measure differences in attitudes to this pandemic across various demographic groups of young adults living inside and outside of Dhaka. The predictors of optimistic attitudes toward COVID-19 also have been investigated. The study is cross-sectional in nature using data from the members of Secondary and Intermediate Level Students’ Welfare Association (SILSWA). Participants (n = 700) self-reported their attitudes toward controlling and defeating the pandemic. ANOVA and a two-sample t-test were utilized to find the differences in the mean attitude across demographic groups. Predictors of attitudes toward COVID-19 were searched using multivariate logistic regression. Psychologically distressed participants showed more negative attitudes toward winning over COVID-19 than participants with good mental health both inside and outside of Dhaka. Participants inhabiting in Dhaka demonstrated less optimism for controlling and beating the pandemic. Less psychological distress [AOR=0.51; 95 per cent CI: 0.35, 0.76; p=0.001] found to be the significant predictors of an optimistic attitude of young adults. Dissemination of précised and accurate information regarding COVID-19 coupled with mental health intervention based on necessity can improve the attitudes of young adults.