Does boredom increase risk behaviors in real-world settings, and if so, might it contribute to failure to comply with public health guidelines during the COVID-19 pandemic? In a large cross-national sample of 63,336 community respondents from 116 countries, we examined the prevalence of lockdown-related boredom during the initial outbreak of COVID-19, as well as its demographic and situational predictors. Boredom was higher in countries with more COVID-19 cases, more stringent lockdown policies, and lower GDPs, as well as among men and less educated/younger adults. Additionally, we examined whether “pandemic boredom” predicted longitudinal decreases in social distancing behavior (and vice versa; n = 8031). We found little evidence that changes in boredom predict individual public health behaviors (handwashing, staying home, self-quarantining, avoiding crowds) over time, or that such behaviors had any reliable longitudinal effects on boredom itself. In summary, we found little evidence that boredom affects pandemic health behaviors.