Baseline Practices for the Application of Genomic Data Supporting Regulatory Food Safety

Author:

Lambert Dominic1,Pightling Arthur2,Griffiths Emma3,Van Domselaar Gary4,Evans Peter5,Berthelet Sharon1,Craig Duncan6,Chandry P Scott7,Stones Robert8,Brinkman Fiona3,Angers-Loustau Alexandre9,Kreysa Joachim9,Tong Weida10,Blais Burton11

Affiliation:

1. Canadian Food Inspection Agency, Ottawa Laboratory (Carling), Ottawa, ON, Canada

2. U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD, USA

3. Public Health Agency of Canada, National Microbiology Laboratory, Winnipeg, MB, Canada

4. U.S. Department of Agriculture, Food Safety and Inspection Service, Washington, DC, USA

5. Food Standards Australia New Zealand, Canberra, Australia

6. Commonwealth Scientific and Industrial Research Organisation, Melbourne, Australia

7. Food and Environment Research Agency, Sand Hutton, York, UK

8. Simon Fraser University, Department of Molecular Biology and Biochemistry, Burnaby, BC, Canada

9. European Commission, Joint Research Center, Ispra, Italy

10. U.S. Food and Drug Administration, National Center for Toxicological Research, Little Rock, AR

11. Canadian Food Inspection Agency, Ottawa Laboratory (Carling), Bldg 22, 960 Carling Ave, Central Experimental Farm, Ottawa, ON, Canada K1A 0Y9

Abstract

Abstract The application of new data streams generated from next-generation sequencing (NGS) has been demonstrated for food microbiology, pathogen identification, and illness outbreak detection. The establishment of best practices for data integrity,reproducibility, and traceability will ensure reliable, auditable, and transparent processes underlying food microbiology risk management decisions. We outline general principles to guide the use of NGS data in support of microbiological food safety. Regulatory authorities across intra- and internationaljurisdictions can leverage this effort to promote the reliability, consistency, and transparency of processes used in the derivation of genomic information for regulatory food safety purposes, and to facilitate interactions and the transfer of information in the interest of public health.

Publisher

Oxford University Press (OUP)

Subject

Pharmacology,Agronomy and Crop Science,Environmental Chemistry,Food Science,Analytical Chemistry

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