Free and Total Carnitine in Infant and Adult/Pediatric Nutritional Formulas by Liquid Chromatography/Tandem Mass Spectrometry: First Action 2012.17-Reference-Cited by-同舟云学术

Free and Total Carnitine in Infant and Adult/Pediatric Nutritional Formulas by Liquid Chromatography/Tandem Mass Spectrometry: First Action 2012.17

Published:2013-09-01 Issue:5 Volume:96 Page:1082-1085
ISSN:1060-3271
Container-title:Journal of AOAC INTERNATIONAL
language:en
Short-container-title:

Author:

Starkey Dustin E¹,Denison James E¹,Seipelt C Thomas¹,Jacobs Wesley A¹,Dowell Dawn²

Affiliation:

1. Abbott Nutrition, 625 Cleveland Ave, Columbus, OH 43215

2. AOAC INTERNATIONAL, 481 North Frederick Ave, Gaithersburg, MD 20877-7089

Abstract

Abstract Data from a previously published study in J.AOAC Int. 91, 130–142 (2008) was presented to the Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN) during the AOAC Annual Meeting held in Las Vegas, NV, from September 30 to October 3, 2012. The panel reviewed the data submitted and concluded that the method satisfied the standard method performance requirements established by SPIFAN. Based on this information, the panel approved the method as AOAC First Action. The determination of free carnitine involves dilution and filtration of the sample, followed by determination of L-carnitine by LC/MS/MS. The determination of total carnitine includes a saponification procedure prior to dilution and filtration.

Publisher

Oxford University Press (OUP)

Subject

Pharmacology,Agronomy and Crop Science,Environmental Chemistry,Food Science,Analytical Chemistry

Link

http://academic.oup.com/jaoac/article-pdf/96/5/1082/32423392/jaoac1082.pdf

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