Effects of Thiosemicarbazide on Audiogenic Seizures

Abstract

35 male albino rats were tested for audiogenic seizures and then divided into 5 time-delay groups. These time delays preceded bell-can stimulations following the administration of thiosemicarbazide. It was found that 1-hr. and 5-hr. delays resulted in an increase in the number of seizures. However, all groups returned to their preinjection level of seizures following a week of rest.