Changes in misuse and abuse of prescription opioids following implementation of Extended-Release and Long-Acting Opioid Analgesic Risk Evaluation and Mitigation Strategy

Author:

Bucher Bartelson Becki1,Le Lait M. Claire1,Green Jody L.1,Cepeda M. Soledad2,Coplan Paul M.3,Maziere Jean-Yves4,Wedin Gregory P.5,Dart Richard C.1

Affiliation:

1. Rocky Mountain Poison and Drug Center; Denver Health and Hospital Authority; Denver CO USA

2. Janssen Research and Development; Titusville NJ USA

3. Purdue Pharma; Stamford CT USA

4. RPC Company; Columbus OH USA

5. Upsher-Smith Laboratories, LLC; Maple Grove MN USA

Funder

REMS Program Companies, a consortium of companies that sponsor the ER/LA opioid analgesic REMS

Publisher

Wiley

Subject

Pharmacology (medical),Epidemiology

Reference35 articles.

1. ER/LA Opioid Analgesics REMS Program Companies Selected important safety information: abuse potential and risk of life-threatening respiratory depression http://www.er-la-opioidrems.com/IwgUI/rems/pdf/important_safety_information.pdf

2. INCB Narcotic drugs report 2013: estimated world requirements for 2014-statistics for 2012 http://www.incb.org/incb/en/narcotic-drugs/Technical_Reports/2013/narcotic-drugs-technical-report-2013.html

3. Increases in drug and opioid overdose deaths-United States, 2000-2014;Rudd;Morbidity and Mortality Weekly Report (MMWR),2016

4. Drug-poisoning deaths involving opioid analgesics: United States, 1999-2011;Chen;National Center for Health Statistics Data Brief 2014; no 166

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