Hypericum perforatum Reduces Paracetamol-Induced Hepatotoxicity and Lethality in Mice by Modulating Inflammation and Oxidative Stress-Reference-Cited by-同舟云学术

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Hypericum perforatum Reduces Paracetamol-Induced Hepatotoxicity and Lethality in Mice by Modulating Inflammation and Oxidative Stress

Published:2015-04-08 Issue:7 Volume:29 Page:1097-1101
ISSN:0951-418X
Container-title:Phytotherapy Research
language:en
Short-container-title:Phytother. Res.

Author:

Hohmann Miriam S. N.¹,Cardoso Renato D. R.¹,Fattori Victor¹,Arakawa Nilton S.²,Tomaz José C.³,Lopes Norberto P.³,Casagrande Rubia²,Verri Waldiceu A.¹

Affiliation:

1. Department of Pathology, Biological Science Centre; State University of Londrina; Londrina PR Brazil

2. Department of Pharmaceutical Sciences, Health Sciences Centre; State University of Londrina; Londrina PR Brazil

3. Núcleo de Pesquisa em Produtos Naturais e Sintéticos, Departamento de Química e Física, Faculdade de Ciências Farmacêuticas de Ribeirão Preto; Universidade de São Paulo; Av. do café, s/n, Campus universitário, Monte Alegre 14040-903 Ribeirão Preto SP Brazil

Funder

CNPq

CAPES

MCTI/SETI/Fundação Araucária

Parana State Government

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ptr.5350/fullpdf

Reference10 articles.

1. The hepatoprotective effects of Hypericum perforatum L. on hepatic ischemia/reperfusion injury in rats;Bayramoglu;Cytotechology,2014

2. St. John's wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse;Bray;Toxicol Sci,2002

3. Effects of Hypericum perforatum extract in a rat model of ischemia and reperfusion injury;De Paola;Shock,2005

4. Hyperforin is a novel type of 5-lipoxygenase inhibitor with high efficacy in vivo;Feisst;Cell Mol Life Sci,2009

5. 5-Lipoxygenase deficiency reduces acetaminophen-induced hepatotoxicity and lethality;Hohmann;BioMed Res Int,2013

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