Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response-Reference-Cited by-同舟云学术

Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response

Published:2016-03-04 Issue:5 Volume:63 Page:1592-1607
ISSN:0270-9139
Container-title:Hepatology
language:en
Short-container-title:Hepatology

Author:

Sunami Yoshiaki¹²,Ringelhan Marc³⁴⁵,Kokai Enikö²,Lu Miao¹,O'Connor Tracy⁴,Lorentzen Anna⁴,Weber Achim⁶,Rodewald Ann-Katrin⁶,Müllhaupt Beat⁷,Terracciano Luigi⁸,Gul Sarah²,Wissel Sebastian²,Leithäuser Frank⁹,Krappmann Daniel¹⁰,Riedl Petra¹¹,Hartmann Daniel¹,Schirmbeck Reinhold¹¹,Strnad Pavel¹²,Hüser Norbert¹,Kleeff Jörg¹,Friess Helmut¹,Schmid Roland M³,Geisler Fabian³,Wirth Thomas²,Heikenwalder Mathias⁴¹³

Affiliation:

1. Department of General Surgery, Klinikum rechts der Isar; Technical University Munich; Munich Germany

2. Institute of Physiological Chemistry; University of Ulm; Ulm Germany

3. Department of Internal Medicine II, Klinikum rechts der Isar; Technical University Munich; Munich Germany

4. Institute of Virology; Technical University Munich/Helmholtz Zentrum Munich; Munich Germany

5. German Center for Infection research (DZIF), Munich partner site; Munich Germany

6. Institute of Surgical Pathology; Zürich Switzerland

7. Department of Gastroenterology and Hepatology; University Hospital Zürich; Zürich Switzerland

8. Institute of Pathology; University Hospital Basel; Basel Switzerland

9. Institute of Pathology; University Medical Center Ulm; Ulm Germany

10. Research Unit Cellular Signal Integration; Helmholtz Zentrum Munich; Munich Germany

11. Department of Internal Medicine I; University Medical Center Ulm; Ulm Germany

12. Department of Medicine III and IZKF; University Hospital Aachen; Aachen Germany

13. Division of Chronic Inflammation and Cancer; German Cancer Research Center (DKFZ); Heidelberg Germany

Funder

DZIF (German Center for Infection Research)

Else-Kröner-Forschungskolleg

ERC Starting Grant (LiverCancerMechanism

Stiftung für Biomedizinische Forschung

Helmholtz Alliance Preclinical Cancer Center

Publisher

Wiley

Subject

Hepatology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/hep.28435/fullpdf

Reference50 articles.

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4. A lymphotoxin-driven pathway to hepatocellular carcinoma;Haybaeck;Cancer Cell,2009

5. IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis;Maeda;Cell,2005

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