Rapid structure identification of nineteen metabolites of ondansetron in human urine using LC/MS n-Reference-Cited by-同舟云学术

Rapid structure identification of nineteen metabolites of ondansetron in human urine using LC/MS n

Published:2019-07-24 Issue:10 Volume:33 Page:
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Duan Mingyu¹²,Qin Li¹,Zhong Dafang³,Zhang Peng¹

Affiliation:

1. Wuya College of InnovationShenyang Pharmaceutical University Shenyang China

2. Bioanalysis Center, Quarkman Pharmaceutical Technology Co., LTD, Benxi, Liaoning, China, Quarkman Pharmaceutical Technology Co., LTD, A1 Innovation Park, New and High‐Tech Development Zone Benxi Liaoning China

3. State Key Laboratory of Drug ResearchShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, Shanghai Institute of Materia Medica, Chinese Academy of Sciences Shanghai China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.4618

Reference19 articles.

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2. Characterisation of the cytochrome P450 enzymes involved in the in vitro metabolism of granisetron.

3. Determination of Ondansetron in Plasma and Its Pharmacokinetics in the Young and Elderly

4. Multiple forms of cytochrome P450 are involved in the metabolism of ondansetron in humans;Dixon C. M.;Drug Metabolism and Disposition,1995

5. Assignments of1H and13C NMR spectral data for ondansetron and its two novel metabolites, 1-hydroxy-ondansetron diastereoisomers

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